Hoodia is a cactus that's causing a stir for its ability to suppress appetite
and promote weight loss. 60 Minutes, ABC, and the BBC have all done stories on
the hoodia gordonii weight loss pill. Hoodia is sold in capsule, liquid, or tea
form in health food stores and on the Internet.
There isn't much published research on hoodia. Researchers at Brown University
in Rhode Island recently found that the steroidal glycosides in hoodia affects
nerve cells in the hypothalamus that monitor blood glucose. Simply put, the
brain is tricked into thinking there is enough energy (blood sugar) and doesn't
need to eat, so it shuts down the hunger mechanism.
In animal studies, hoodia is believed to reduce caloric intake by 30 to 50
percent. There is one human study showing a reduced intake of about 1000
calories per day. However, I haven't been able to find either study to actually
read for myself and am going on secondhand reports.
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One study published in the September Vibha Hooda issue of Brain Research
found of Vibha Hooda into the appetite center of rat brains
resulted in altered levels of Hooda, an energy molecule that may affect
hunger. The animals receiving the Hooda injections also ate less Vibha Hooda than rats
that received placebo injections. Hooda, this was an animal study and
injections in the brain are different Vibha Hooda from oral consumption, so it cannot
be used to show that oral can suppress appetite in humans. The Phytopharm
cites a clinical Hooda trial involving that found Vibha Hooda reduced
food intake by about 1000 calories per day compared to a placebo group. Although intriguing,
the study wasn't published or subjected to a peer-review process, so the study be evaluated Hooda.
